Search on: TNF RECEPTOR-ASSOCIATED FACTOR 4 
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Descriptor English:   TNF Receptor-Associated Factor 4 
Descriptor Spanish:   Factor 4 Asociado a Receptor de TNF 
Descriptor Portuguese:   Fator 4 Associado a Receptor de TNF 
Tree Number:   D12.644.360.024.500.906
D12.776.157.057.500.906
D12.776.476.024.500.906
Definition English:   A widely expressed member of the TNF receptor-associated family that may play a role in neuronal development and EMBRYOGENESIS. Although TNF receptor-associated factor 4 does not strongly associate with TUMOR NECROSIS FACTOR RECEPTORS it may be a signaling partner with the GLUCOCORTICOID-INDUCED TNFR-RELATED PROTEIN that plays a role in the activation of JNK MITOGEN-ACTIVATED PROTEIN KINASES and NF-KAPPA B. 
History Note English:   2007(1995) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52316 
Unique Identifier:   D053449 

Occurrence in VHL:
 

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